Engineering microenvironments to control stem cell fate and function ∗
نویسنده
چکیده
2.1. Immobilization of signaling factors as a mechanism to control local concentration . . . . . . . . . . . . . 3 2.2. Sequential factors to program stem cell differentiation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 2.3. Factors secreted or presented from differentiated cells within the niche . . . . . . . . . . . . . . . . . . . . . . 4 3. Direct cell-cell contact . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 4. ECM presents important biochemical and mechanical cues to stem cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 5. Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 6. Acknowledgements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 7. References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
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Constructing stem cell microenvironments using bioengineering approaches.
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